Wednesday, June 4, 2014

The Reason for the Loss of Bone Mineral Density in Space (weightless environment - microgravity) and on the Earth

Loss of Bone Mineral Density in Space (weightless environment – microgravity)

The absence of mechanical stimulation, which on the Earth is produced by working against gravity and by our own body weight, is the cause of the loss of bone density in Space (weightlessness - microgravity).
There are two main types of mechanical stimulations which are absent in space.
1) Mechanical stimulation induced by our own body weight. (In a weightless environment, the body has mass but doesn’t have weight.) On the Earth, even in a laying down position, the body gets some amount of mechanical stimulation because the weight of each body particle above provides mechanical stimulation to the below particles. The particles which are below bear the weight of the particles which are above.
2) Mechanical stimulations induced by working against the gravity (against the pull of gravity). Standing, walking, running and jumping are examples of working against the pull of gravity. Actually, by performing any physical activity, the most effort we put in is to support and carry our own body weight.
The most mechanical stimulation induced by working against gravity, like standing, walking, running and jumping, etc, comes from the foot-ground impact forces
There is no foot-ground impact force in a weightless environment (Microgravity). (Hitting the floor with the foot in the Space Station will result in hitting the ceiling with the head.).

Loss of Bone Mass and Bone Mineral Density on Earth (1G Environment)

Insufficient physical activity and/or extreme efficiency in performing locomotion (walking and running) is the cause of the loss of bone mineral density on the Earth. (The competitive marathon runners are affected by the low bone density.)
 
The Biological Basis of Bone MASS and Bone Mineral DENSITY GAIN
 
1)    Excessive (excessive strength and/or excessive duration) mechanical stimulation causes (increased) inflammation of the bones.
 
2)    Sufficient mechanical stimulation (sufficient strength and sufficient duration) maintains normal inflammation (homeostasis).


The Biological Basis of Bone MASS and Bone Mineral DENSITY LOSS
 
1)    Insufficient mechanical stimulation (insufficient strength and/or insufficient duration) causes a decrease in inflammation below the level required for maintaining existing bone mass and bone density. 

MECHANICAL STIMULATION – INFLAMMATION model explains the density loss/gain of all bones, including the bones of the human skull in Space (weightless environment - microgravity) and on the Earth (1 G environment).
1) Bones can increase in size and density. 
2) Bones can increase in size but the bone density decreases
3) Bones can decrease in size and density. 
4) Bone size can decrease, but bone density increases. 

Copyright 2014 – 2021 Luka Tunjic

Luka Tunjic is the author of the book “Mechanical Stimulation Low-Grade Inflammation Weight Gain

Sunday, January 12, 2014

Type 1 Diabetes and Modern Science of Biomechanics (Ground-breaking Type 1 Diabetes Research)

For the most of 2013, I spent most of my time working on type 1 diabetes. It is from an idea that I came across in 2005. Here is the contents of my work/research on Type 1 Diabetes from 2005 until the end of 2013.  

The research is spread over 12 web pages and each page will be updated during 2014. 

The purpose of publishing this research is to point out that Type 1 Diabetes can be prevented and cured only with nonsurgical and non-pharmaceuticals means. 

This research on Type 1 Diabetes by no means suggest to people with type 1 Diabetes to do or not to do something in order to treat or cure type 1 diabetes. For now, the only purpose of publishing this research on the internet is to initiate a clinical trial conducted by medical scientists involved in the research of diabetes, along with people involved in researching biomechanics like chiropractors, osteopaths, physiotherapists, podiatrists, etc.
 

Research Paper Contents


1) Postural Profile of People with Type 1 Diabetes - web pages 1 

No one before took notice that people affected with type 1 diabetes share certain postural characteristics that has not been found in people without Type 1 diabetes      (To read more click here)

2) Postural and Musculoskeletal Characteristics of Normal Weight People without and with Type 1 diabetes – web page 2 -

The graphic illustrations in the article Profile of the musculoskeletal characteristics of normal weight people without and with Type 1 diabetes points out the postural and musculoskeletal differences between people with and without Type 1 diabetes. (To read more click here)

3)  Spontaneous Remission of Type 1 Diabetes    – web page 3 -

There is almost no attention paid to the examples of spontaneous remission of type 1 diabetes, but there are quite a few examples of temporary and even permanent remission of type 1 diabetes. (To read more Click Here)

4) Obesity and Type 1 Diabetes – Obesity Protect against Type 1 Diabetes?   – web page 4 -

Actually, obesity is not what protects us from Type 1 diabetes, but something else that goes along with obesity.

The first step to understand what protects us from developing Type 1 diabetes is to analyse and compare the postural and musculoskeletal characteristics of obese, overweight and normal weight people. People with certain postural characteristic can’t get obese, it doesn't matter how much they eat and how physically inactive they are. (To read more click here)

5) Weight Loss and Type 1 Diabetes – Weight Loss Linked to Type 1 Diabetes?   – web page 5 -

The fact is that children experience weight loss around the time of their diagnosis with Type 1 Diabetes. This leads to the conclusion that the body weight, whether it is underweight, overweight or obese, is not related or even correlated with the development of Type 1 diabetes, but weight loss is connected with the development of type 1 diabetes. (To read more click here)

6) Insulin Therapy and Weight Gain     – web page 6 -

The theory that insulin enables the glucose to enter the cells and the glucose that has not been used is accumulated as fat is not only absolutely wrong, but it is responsible for the huge rise in the practice of deliberately skipping insulin in order to prevent or to lose weight. Before that theory, that practice was unknown. (To read more click here)

7) Exercises Induced Low Blood Sugar (Hypoglycaemia) and High Blood Sugar (Hyperglycaemia)   – web page  7 -

The most dangerous post-exercise hypoglycaemia happens during night sleep (night-time hypoglycaemia or nocturnal hypoglycaemia). Night time hypoglycaemia (or nocturnal hypoglycaemia) can be fatal. Actually, night time hypoglycaemia has been considered to be responsible for a large proportion of sudden deaths in young T1DM patients.

Understanding post-exercises weight loss is an essential condition to understand and prevent post-exercises hypoglycaemia, including night time hypoglycaemia. (To read more click here) 
 

Appendix

 
  I.     Type 1 Diabetes in American Indians and Alaska Natives   - web page 12 - 1 - 

II.     Type 1 Diabetes among the Amish    - web page 12 - 2 - 

   III.        Why more and more Children are Developing Type 1 Diabetes    - web page 12 - 3 - 

   IV.        Type 1 Diabetes in Animals   - web page 12 - 4 - 

    V.        Hypotheses about the Causes for Type 1 Diabetes in Very Young Children, Older Children and Fully Grown Adults   - web page 12 - 5 -
 

Warning! Any possible attempt to induce postural and/or musculoskeletal changes in order to treat and cure Type 1 diabetes without understanding the role of biomechanics in Type 1 diabetes may cause serious or fatal consequences.

Here are just a few reasons for that;      

1.  Adverse postural changes is one factor of Type 1 diabetes.

2.  Adverse musculoskeletal changes is another factor of Type 1 diabetes.

3.  Faulty biomechanics is an undivided factor with adverse postural and musculoskeletal changes.

4.  Reduced size of the pancreas in Type 1 diabetes.

5.  Low bone mineral density in Type 1 diabetes.

6.  Exercises in some cases induce hyperglycaemia - high blood sugar and in some cases induce hypoglycaemia - abnormally low level of sugar (glucose) in the blood.

6 – The real danger of death while sleeping. “One in 20 type 1 diabetics die in their sleep due to a sudden drop in their blood sugar.”  

Please note: The purpose of publishing this research on the internet is to initiate a clinical trial conducted by medical doctors involved in the research of diabetes along with people involved in biomechanical research like chiropractors, osteopaths, physiotherapists, podiatrists, etc.

Copyright 2014 – 2021 Luka Tunjic

Luka Tunjic is the author of the book “Mechanical Stimulation Low-Grade Inflammation Weight Gain